Thursday, October 31, 2019
One page reflection on the learning outcomes Coursework
One page reflection on the learning outcomes - Coursework Example The fin geometry has significant impact on the performance of a car radiator. There are four major geometric flow configurations for radiators. The geometry of the fin determines the amount of heat lost from the car engine to the atmosphere and hence determines the performance of a car radiator. Car radiator normally uses crossflow two-stream geometry. The heat transfer performance of a radiator can be determined by calculating the number of Nusselts. The value of Nusselt number increases with increase in as the Reynolds number. The performance of the heat exchanger increases with increase in the number of Nusselts. As such, the number of Nusselts is directly proportional to the performance of the heat exchanger. This assignment is makes an invaluable contribution to the UniSA graduate qualities by equipping the graduates with essential knowledge for manufacturing radiators, particularly car radiators and developing innovative ideas to improve the radiator, which is one of the most crucial components of the car
Tuesday, October 29, 2019
Nietzche's Philosophical Understanding of Truth Essay
Nietzche's Philosophical Understanding of Truth - Essay Example However diverse the interpretations of the different scholars may be, they all agree that Nietzsche's philosophy is perspectival. Nietzschean thought claims that there is no singular truth or absolute truth. There is instead a multiplicity of truths. His philosophy states that there is no singular platform or vantage point from which absolute truth could be seen. However, there is also a multiplicity of perspectives, each with their distinct way of presenting the truth. Many scholars have searched for solutions to what appear to be cnradictions arising from Nietzsche's works. This paper however, only aspires to give an interpretation of his thoughts and philosophies. So that the human individual may survive and preserve his condition, given that he has none of the accouterments of beasts armed with the most deadly of natural weapons with which to defend themselves and dominate weaker specimen, Man has resorted to his intellect using the art of dissimulation. It is through "deception, flattery, lying, deluding, talking behind the back, putting up a false front, living in borrowed splendor, wearing a mask, hiding behind convention, playing a role for others and for oneself - in short, a continuous fluttering around the solitary flame of vanity", that Man is able to not only survive but also prevail over other species and his fellowmen. Given that man possesses such a nature, and such nature arises from necessity, it becomes a contradiction that Man should also possess a drive to find truth. Nietzsche states that men do not comprehend the truth through their senses, but merely receives stimuli through them. He is also deceived by his dreams, and does not have a full comprehension of himself since there are many things in his biological constitution that naturally could not be seen. Since Man's nature, mind and his senses and tools of perception do not fully reveal the truth, Nietzsche asks from where does the drive to find truth emanate As an individual needs to preserve himself against others, he also desires their company, being the social being that he is. As such, though he utilizes dissimulation for the purpose of self-preservation, he also tries to eliminate the most flagrant of this method. This compromise gives root to Man's need to find truth. Designations are given to all things and these assignations become the basis for the truths as individuals agree they should be. It is upon these designations that the difference between truths and lies are based. A person who lies is someone who applies the designation or word for one thing to describe another. If this results to harm for another individual or society, then he will be distrusted and even ostracized. Man responds in this way to lies because he is harmed by the commitment of fraud, and not the act of lying itself. It is not deception which is abhorred or condemned but the consequential negative effect it brings upon them. The greater the degree of harm, the more hostile society becomes to the fraudulent person. But the question remains on whether the words used as designations for truths are themselves consistent with what is "absolutely true". Nietzsche describes words as merely "the copy in sound of a nerve stimulus". The more incongruent or distant a word is from the nerve stimulus it is supposed to represent, the more false it becomes. Words therefore are arbitrary assignments which represent
Sunday, October 27, 2019
Free Trade Between Bhutan and India
Free Trade Between Bhutan and India Analyze the impact of free trade with India on Bhutan by describing free trades impact on agriculture. Free trade is the term given to trade between nations that takes place without the imposition of barriers in the form of tariffs, quotas or other measures by governments or international organizations. Free trade is generally considered by economists to be beneficial to international trade by encouraging competition, innovation, efficient production and consumer choice (Just $ Antle, 1990). Free trade brings positive impacts to the particular country like international community by enabling countries to specialize in certain goods and services and increase their productivity. Free trade also brings problems or negative impacts like domestic industries by increasing competition and increasing business risk. Thus free trade is Trade is an essential part of the economy with high benefits as well as negative impact to the nation. With this I will be analyzing the impact of free trade with India on Bhutan describing free trades impact on agriculture. Agriculture has been realized as a source of livelihood of vast majority of people in developing countries, despite its declining share in many national economies during the past decades. For farmers and their families, agriculture is a source of food, medicines, housing, saving, etc. in which they can also convert farm outputs into income for their childrenââ¬â¢s education and to meet other needs (Bhandari, 2004). In social terms, agriculture can also be a source of freedom, knowledge, and social network and relationships. Therefore, unlike other sectors, agriculture is multifunctional. It is a source of income, self-employment and social safety net for rural population. It is fundamental to food security although it can be argued that not all people in food abundant countries were secured food access. In addition, the way agriculture is developed is closely linked to biodiversity, natural resources, local knowledge and cultures. The primary goals of agriculture in Bhutan are to raise the per capita income of the people living in rural areas, to enhance self-sufficiency in staple crops, and to increase the productivity per unit of farm labor and agricultural land. For countries that have a competitive agricultural sector, the expansion of international trade in agricultural commodities can have a growth-enhancing effect and improve their trade balance. These benefits should be balanced against other potential impacts on the right to food. As Bhutan being developing country, people depends more on agricultures sectors rather than manufacturing sectors. However, free trade with India has a great advantage for Bhutan. As India [SD1]is not only Bhutans main development partner but also its leading trade partner. A free trade regime exists between India and Bhutan enables Bhutan to specialize in the production of those commodities in which they have a comparative advantage (Wangyal, 2000). For example, Production of cash crops such as apple, orange and cardamom have increased and have become profitable. This helps country to take advantage of efficiencies generated from economies of scale and increased output. International trade increases the size of a firmââ¬â¢s market, resulting in lower average costs and increased productivity, ultimately leading to increased production. It also benefits the consumers in the domestic economy as they can now obtain a greater variety of goods and services. The increased competitions ensure goods and services, as well as inputs, are supplied at the lowest prices. By concentrating on agricultures sectors, it may be possible for countries and the firms operating in their territory to build up economies of scale that lower their costs and boost productivity. Generally, larger organizations may compete more efficiently on the international market by keeping control over their costs of production and managing their supply chain to reduce transport and inventory costs. International trade increases competition as domestic industries must compete with foreign firms in the same industry as well as other firms in their own country[SD2]. This compels domestic industries to look for ways to keep costs down by operating more efficiently. This gives them an incentive to innovate and look for improved products, processes and marketing methods (Desia.1990). This constant search for new ideas and technology enables them to compete on the international market. When Bhutan involved in free trade with India, it experience rising living standards, increased real incomes and higher rates of economic growth. Employment will increase in exporting industries and workers will be displaced as import competing industries fold in the competitive environment. Wit h free trade many jobs have been created, which can absorb the unemployment created through restructuring as firms close down. When Bhutan sells exports overseas it receives foreign currency from the countries that is India that buys the goods. This money is then used to pay for imports such as electrical equipment and cars that are produced more cheaply overseas. However the development of global supply chains results in an increased dependency on international trade, for both net food-exporting countries and for net food-importing countries. This may lead to a loss of export revenues for agricultural exporters when the prices of export commodities go down, as well as to threats to local producers when low priced imports arrive on the domestic markets, against which these producers are unable to compete. Conversely, when prices rise, the dependency of low income net food importing countries on the food commodities they buy on the international markets can lead to balance of payments problems against which the mechanisms currently established within the WTO have failed to protect them. The expansion of global supply chains increases the role of large transnational corporations of the agro food sector, vis-à -vis both producers and consumers. This creates a potential for abuses of market power in increasingly concentrated global food supply c hains. According to Rung (1993), the expansion of trade in agricultural commodities has potential impacts on the environment and on human health and nutrition, impacts that usually receive little attention in international trade discussions, despite their close relationship to the right to adequate food. Free trade can lead to pollution and other environmental problems as companies fail to include these costs in the price of goods in trying to compete with companies operating under weaker environmental legislation in some countries (Anderson, 1991). International markets are not a level playing field as countries with surplus products may dump them on world markets at below cost. Some efficient industries may find it difficult to compete for long periods under such conditions. Further, countries whose economies are largely agricultural face unfavorable terms of trade whereby their export income is much smaller than the import payments they make for high value added imports, leading to large CADs and subsequently large foreign debt levels. And other policy that government can adopt is to increase the import tariffs, which means charging price and imposing high taxes on import items. Free trade is an element of expanding economic growth and opportunity, since it broadens new markets. It also includes economic interaction among different nations involving the exchange of goods and services, that is, exports and imports. Free trade has both pros and cons for the country, since it involves the transaction of goods and services between different countries. There fore free trade may bring benefits to some countries for example, developed countries can have more benefits and it has also negative impacts epically for the underdeveloped or developing countries. What policy should Bhutan adopt to take advantage of free trade with India? Trade is an essential part of the economy and has great potential to create employment. The policy on trade shall focus on creating an enabling environment for more robust trade (Rostow, 1916). This will encompass simplifying administrative procedures and deregulating activities wherever feasible. The successful implementation of the free trade Policy would lead to growth in the trade sector both at the import and export fronts. This will invariably require improvement in domestic laws, rules and regulations that would boost investor confidence. The Royal Government shall facilitate trade between Bhutan and India in order to have economic development of the country and shall be the guiding document for all ministries and agencies to stimulate the economy growth and more importantly, to ensure that growth takes place in consonance with the principles of GNH. This Policy provides the basis for government intervention to enhance productivity of the economy as a whole. Wherever necessary , policies, laws, rules and regulations shall be harmonized or amended in line with the provisions of the Economic Development Policy. The Royal Government of Bhutan to have an advantage of free trade with India, the government should have secure transit rights for traffic in transit to facilitate international trade. Transport agreements with neighboring countries to avoid transshipment at the border should be negotiated. The Royal Government should ensure the establishment of a sound distribution system in the country through a network of dealers/wholesalers and retailers with priority accorded towards ensuring the flow and availability of essential commodities and goods in all parts of the country. And also efforts should be made to harmonize customs documentation, procedures and formalities through bilateral and regional initiatives. The Royal Government shall develop the required policy framework that will encompass anti-dumping measures, anti-subsidies and safeguards legislations. The reasons or policy to have trade advantage from India is through export of goods and services. Bhutan should use all tools of export and market promotion, including diplomacy, market studies, market information, branding, advertisements, product launches, trade fairs, expositions and trade missions to assist the private sector to establish markets for their products. Nation branding by leveraging the positive attributes of the country shall be a key instrument harnessed for creating Brand Bhutan in export markets. Exporting more goods and services helps country to generate more income and this income and revenue can be use for the growth and development of the country. The theory of comparative advantage first put forward by David Ricardo in the first part of the nineteenth century demonstrated that countries may boost their production by specializing in those industries for which their opportunity cost is lower than for their competitors. By engaging in international trade, count ries may then export those goods or services that they are most efficient in producing and import the items which other countries may produce more efficiently. Incase of Bhutan, the major items of exports from Bhutan to India are electricity (from Tala, Chukha and Kurichhu Hydroelectric Projects), base metals and articles, minerals, vegetable fat and oils, alcoholic beverages, chemicals, cement, timber and wood products, cardamom, fruit products, potatoes, oranges and apples, raw silk, plastic and rubber products Gyeltshen, ( 1998). So in this case Bhutan can specialize on those product which has comparative advantage cost. The Agreement on Trade and Commerce also provides for duty free transit of Bhutanese merchandise for trade with third countries. According to Anderson Tyers (1991), the entry and exit point for bilateral trade is given in the Trade Agreement. There fore government should encourage country to exports more of goods as it is the source income. Exports of goods and services to other countries, helps in providing foreign currency which help in importing the advanced technologies for the benefits of the country. So royal gove rnment should develop and adopt the export promotion strategy to have an advantage of free trade with India. Free trade involves exchange of goods and services that is exports and imports of goods. Exporting more goods is helpful for the country but importing more goods is not goods. This is because when Bhutan imports more goods and services from India, our country may become too dependent, this leaves the economy vulnerable to fluctuations in the price of that commodity. A particular industry in a country can fall into decline, resulting in factory closures and unemployment. The labor market is not fully flexible, and workers may have difficulty retraining for other industries or moving to other locations to find work. Structural unemployment may therefore cause problems for a countryââ¬â¢s economy (Huntington, 1968). There fore Bhutan should adopt a policy known as import restriction to reduce the number of imports from India and other countries. Import restriction helps in specialization of goods in the particular country. Major exports from India to Bhutan are high speed diesel, fer rous products, motor spirit including aviation spirit (petrol), rice, ferrous waste and scraps, wood charcoal, hydraulic turbines, coal, briquette and similar solid fuel of coal, coke and semi coke of coal, bar and rods of iron and non alloy steels, corrugated iron and non alloy steel sheet, soybean oil, milk powder etc. So imports should reduce imports by import substitution and import restriction policy. The main purpose of Bhutan keeping relation with India through free trade is to promote economic development of the country. To have economic growth and development in the country, Bhutan should frame certain policy which helps in taking free trade advantage from other countries. Lack of policy may has a negative effects to country as Bhutan being a developing nation, there is chances of domination, loss of countries sovereignty, unemploymentââ¬â¢s, inequalities and many problems. So overcome those problems in the country, governments should frame and adopt different policies in taking advantage from India through free trade. References Anderson, K. Tyers, R. (1991). Global Effects of Liberalizing Trade in Farm Products. New York: Harvester Wheat sheaf.pp.113 Anderson, K. (1991). Agricultural trade liberalization and the environment: A global perspective. The World Economy, Vol. 15, pp. 153-171. Bhandari, S., (2004). TRIPS Related Legislation Multilateral Trade Integration. Human Development in Nepalâ⬠prepared for Multilateral Trade Integration. Desia, G. (1990). Fertilizer policy issues and sustainable agricultural growth in developing countries. IFPRI Policy Briefs. Washington. Gyeltshen, T. (1998). India-Bhutan Trade Relation. Economics Association Papers and Proceedings, Vol. 80, No. 20, pp. 197-202. Huntington, S.P (1968). Political Order in Changing Societies. New Haven: Yale University Press. Just, R. J. Antile. (1990). Interactions between agricultural and environmental policies: A conceptual framework. American Economics Association Papers and Proceedings, Vol. 80, No. 20, pp. 197-202. Rostow, W. W. (1916). The World free trade; History and prospect. United States of America; London. Rung, C.F. (1993). Trade liberalization and environmental quality in agriculture.International Environ-mental Affairs, Vol. 5, No. 2, pp. 95-128. Wangyal, T., (2003). Reconciling Rhetoric and Reality: An Assessment of the Impact of WTO.pp.112 [SD1]http://library.fes.de/pdf-files/bueros/genf/06819.pdf [SD2]http://www.brighthub.com/office/finance/articles/122806.aspx
Friday, October 25, 2019
Tourettes Syndrome and the :: Biology Essays Research Papers
Tourette's Syndrome and the "I" Function Tourette's syndrome is characterized by a presentation of verbal and motor tics. The first descriptions of the syndrome, involving symptoms similar to Tourette's, were reported in the nineteenth century. For most of the twentieth century TS was thought to be a psychiatric disorder because of the ability the patients had to suppress their tics. In the past twenty years more biological factors have been introduced in the study of the syndrome, arising from the use of pharmacological treatment and the discovery of hereditary patterns of the disorder. In the diagnosis of Tourette's Syndrome the concept of involuntary tics has become hard to define. Many patients experience a volitional aspect of the tics, "a capitulation to an internal urge for motor discharge accompanied by psychological tension and anxiety Patients who are afflicted with Tourette's syndrome can only describe their symptoms by using terms associated with the "I" function, the consciousness of self and relation to one's environment, and many of their symptoms are associated with or affect the function of their self. This can imply that what ever is causing the symptoms of Tourette's is subsequently affecting the part of the nervous system that controls the self and the "I" function. Most of the studies done on the neuropathology of Tourette's syndrome (TS) have been focus on the basal ganglia, a group of nuclei located mostly in the diencephelon of the brain, a region beneath the cortex. This area has been classically associated with involuntary movement and tic disorders such as Parkinson and Huntington's disease. The neural circuits formed by the basal ganglia and the thalamus are critical for normal function and hypothesized to be required for the planning of movement ranging from simple to complex. Though what these pathways actually do is still very vague the basal ganglia has been found, in normal circumstances, to exert an inhibitory influence on the thalamus. Disruption of this inhibition could correspond with TS in which the making of uncontrolled and unplanned movements are involve. There is evidence that patients with Tourette's syndrome have some structural abnormalities in the region of the basal ganglia, mainly TS patients showed a comparative size reduction in the basal ganglia. There are various different behaviors through which Tourette's syndrome presents itself. The diagnostic categories of TS depend on the presence of tics, alone, although patients with Tourette may have mental or behavioral disorders, which over shadow the severity or impairment on normal function of the tics.
Thursday, October 24, 2019
The global environment
The protection of the planetary environment has become one of the cardinal aims of the international community in recent decennaries. The major environmental issues such as clime alteration, ozone depletion, deforestation acid rain and loss of biodiversity are planetary in range. [ 1 ] Climate alteration is a planetary long-run job ( up to several centuries ) that involves complex interactions with environmental, economic, political, institutional, societal and technological procedures. The international community has taken legal stairss to battle clime alteration. The United Nations Framework Convention on Climate Change ; the Kyoto Protocol and other clime related instruments are all legal instruments which target clime alteration extenuation. These legal instruments have created a differentiation in footings of duties and duties between the developed and the development states through the rule of common but differentiated duties. [ 2 ] The rule of common but differentiated duty has developed from the application of equity in general international jurisprudence for the particular demands of developing states which must be taken into history in the development, application and reading of regulations of international environmental jurisprudence. [ 3 ] The Framework Convention on Climate Change ( Climate Convention ) ,1 signed at the 1992 United Nations ââ¬Å" Earth Acme â⬠in Rio de Janeiro, is the first international legal instrument to turn to clime alteration and is arguably the most comprehensive international effort to turn to inauspicious alterations to the planetary environment.Principle 7 [ 4 ]States shall collaborate in a spirit of planetary partnership to conserve, protect and reconstruct the wellness and unity of the Earth ââ¬Ës ecosystem. In position of the different parts to planetary environmental debasement, States have common but differentiated duties. The developed states acknowledge the duty that they bear in the international chase of sustainable development in position of the force per unit areas their societies place on the planetary environment and of the engineerings and fiscal resources they command. he overruling end of the Convention is the ââ¬Å" stabilisation of nursery gas concentrations in the ambiance at a degree that would forestall unsafe anthropogenetic intervention ith the clime system. ââ¬Å" [ 5 ] The rule of common but differentiated duties, one of the cardinal constructs of sustainable development, has double foundation ; the force per unit areas developed states topographic point on the planetary environment ; and the engineerings and fiscal resources they command. Though the developed states are loath to acknowledge the first foundation, the developing states have a strong purchase to bring on the former to accept differentiated intervention in their favour. [ 7 ] The contemplation of this rule takes two signifiers: one is ââ¬Å" dual criterions â⬠in environmental protection criterions every bit good as their execution in favour of developing states ; and the other is assistance by developed states for sustainable development of developing states. The impression of common but differentiated duty is comprised of two distinguishable yet mutualist constituents: ( 1 ) common duty and ; ( 2 ) differentiated duty. The first represents the shared duties of two or more States when the inquiry of protection of a specific environmental resource is raised. [ 8 ] The 2nd relates to distinguish environmental criterions which are articulated around legion factors such as particular demands and fortunes, future economic development of states, and the historic part of a state or group of states to the creative activity of an environmental job.Article 10 Kyoto protocol [ 9 ]All Parties, taking into account their common but differentiated duties and their specific national and regional development precedences, aims and fortunes, without presenting any new committednesss for Parties non included in Annex I, but reaffirming bing committednesss under Article 4, paragraph 1, of the Convention, and go oning to progress the execution of these committ ednesss in order to accomplish sustainable development, taking into history Article 4, paragraphs 3, 5 and 7, of the Convention, shall:Formulate, where relevant and to the extent possible, cost-efficient national and, where appropriate, regional programmes to better the quality of local emanation factors, activity informations and/or theoretical accounts which reflect the socio-economic conditions of each Party for the readying and periodic updating of national stock lists of anthropogenetic emanations by beginnings and remotions by sinks of all nursery gases non controlled by the Montreal Protocol, utilizing comparable methodological analysiss to be agreed upon by the Conference of the Parties, and consistent with the guidelines for the readying of national communications adopted by the Conference of the Parties ;F CDBR is illustration of emerging perceptual experiences of equity.Duncan French ( 2000 ) . Developing States and International Environmental Law: The Importance of Diffe rentiated Responsibilities.International & A ; Comparative Law Quarterly,49, pp 35-60 doi:10.1017/S0020589300063958Mustapher, Ntale, Rethinking the Application of the Principle of ââ¬ËCommon but Differentiated Responsibilities ââ¬Ë in the International Climate Legal Framework ( December 6, 2008 ) . Available at SSRN: hypertext transfer protocol: //ssrn.com/abstract=1312282Bharat Agarwal, The Principle Of Common But Differentiated Responsibility In Environmental LawRio Declaration on Environment and Development 1992 United Nations ( UN )United Nations Conference on Environment and Development: Framework Convention on Climate Change, May 9, 1992, art. 2, 31 I.L.M. at 854.Duncan French ( 2000 ) . Developing States and International Environmental Law: The Importance of Differentiated Responsibilities.International & A ; Comparative Law Quarterly,49, pp 35-60 doi:10.1017/S0020589300063958International Environmental Agreements: Politicss, Law and Economics, Springer Netherlands, Vol ume 2, Number 2 / June, 2002, pg. 151-170 www.springerlink.comP. Sands, Principles of International Environmental Law: Models, Standards and Implementation, 1st edn. ( Manchester: Manchester University Press, 1996 ) at 217.KYOTO PROTOCOL TO THE UNITED NATIONS FRAMEWORK CONVENTION ON CLIMATE CHANGE
Wednesday, October 23, 2019
Understanding Nutrition
Al-Quds University Body Fluid Lab. Report Chemical Examination of Urine Prepared By : Lucia Principles Benedict's Test for Reducing Sugars Urinary sugars when boiled in Benedict's reagent reduce copperà sulphateà to a reddish cuprous oxide precipitate in hot alkaline medium, the intensity of which is proportional to the amount of sugar present in the urine. The results are reported as 1+,2+, etc. depending upon theà colourà and intensity of the cuprous oxide precipitate. turbidimetric method protein in urine Quantitative Tests for 24-Hour Specimens. Trichloroacetic acid (TCA) test.The addition of TCA to a urine specimen precipitates the protein in a fine suspension that is quantified spectrophotometrically at 420 nm (nanometers) by comparison with a similarly treated standard. Heat and acetic acid method Heat test: Based on the principle of heat coagulation and precipitation of proteins. If any turbidity appears, add 2 drops of 33% acetic acid. (Acidification is necessary because in alkaline medium heating may precipitate phosphates). If the precipitate is due to proteins, it will increase on acidification and if it is due to phosphates, it will dissolve again.Sulphosalicylicà acid method Urine Protein Sulfosalicylic Acid Precipitation Test (SSA) Principle: Three percent (3%) Sulfosalicylic Acid (SSA reagent) is added to a small and equal volume of clear urine. The acidification causes precipitation of protein in the sample (seen as increasing turbidity), which is subjectively graded as trace,1+, 2+, 3+ or 4+. Bence Jones protein Bence Jones reaction involves heating urine to 140à °F (60à °C). At this temperature, the Bence Jones proteins will clump. The clumping disappears if the urine is further heated to boiling and reappears when the urine is cooled.Other clumping procedures using salts, acids, and other chemicals are also used to detect these proteins. These types of test will reveal whether or not Bence Jones proteins are present, but not how much is present. Hemosiderin Hemosiderin stain is used to indicate the presence of iron storage granules called hemosiderinà by microscopic examination of urine sediment. Granules of hemosiderin stain blue when potassium ferrocyanide is added to the sample. The Prussian blue stain may also be used to identify siderocytes (iron-containing red blood cells [RBCs]) in peripheral blood.The presence of siderocytes in circulating RBCs is abnormal. Urobilinogen This test is based on a modified Ehrlich reaction in which p-diethylaminobenzaldehyde reacts with urobilinogen in a strongly acid medium. Colors range from light pink to bright magenta. Results * Benedict's Test result for cup # G3 : 4+ Brown color appear. * Turbidimetric method result for cup of 24-hrs urine: Tube| Absorbance| Test+test-blank| 0. 058| Standard+water blank| 0. 010| Calculation : Total protein (mg/dl)=At/Ast ? conc. St 0. 058/0. 010 ? 100=580 mg/dl Total protien(mg/24 hrs) =urine protein (mg/dl)? urine volume(ml )/100 = 580? 2000/100)=11600 mg /dl Normal values :0-150 mg/24 hrs * Heat and acetic acid method and Sulphosalicylicà acid method for cup # P4: 4+ precipitation appeared. * Bence Jones protein for cup # P4 : Clear after 15 min of boiling so negative for Bence Jones protein. * Hemosiderin results :Few Hemosiderin granules was seen under Microscope * Urobilinogen result for cup # G3:Negative result (no appearance of red color). Interpretation Benedict's Test for Reducing Sugars Normal urine does not contain any reducing sugar. If protein is present in large amounts, it may interfere with the precipitation of the cuprous oxide.To overcome this problem, precipitate the proteins using 3% SSA filter using aà Whatmanà filter paper and use the filtrate to test the amount of sugar present. As a quality control measure, standards containing known amounts of glucose are prepared in saturated benzoic acid and one of the standards is used every day to check the reliability of the patientâ â¬â¢s results. The standard results may be transformed in the following semi-quantitative way. turbidimetric method protein in urine For turbidimetric methods, there were no apparent problems of comparative bias between human albumin and serum-based materials and urines used in this study.Perhaps this was because all materials were diluted in 9 g/L saline: turbidimetric methods generally suffer from failure of standards and samples to form precipitates identically,and precipitation may not occur at low protein concentrations in urines of high ionic strength. Heat and acetic acid method This test is sensitive enough to detect protein down to a concentration of 2-3 mg%. Ifà an alkalineà urine is boiled, the protein may be converted into the so- called ââ¬Å"alkalineà metaproteinâ⬠, which is not coagulated by heat. Therefore it is always better to acidify the urine before doing this test.If too much acetic acid is added, the protein may be converted to the so-called â⬠Å"acidà metaproteinâ⬠, which is also not coagulated by heat. Therefore the urine should be only mildly acidic. Sulphosalicylicà acid method Theà sulphosalicylicà acid method will not detect protein inà a normalà urine, but will be sensitive enough to detect protein present down to 20mg%. As a quality control measure, a 22g/dl albumin solution can be diluted appropriately with 0. 9 g/dl sodium chloride to get standards containing 20, 50, 200, 500 and 2500 mg/dl proteins.These standards are stable for one month when stored at 2-80C. Bence Jones protein Monoclonal light chain proteinuria (Bence Jones proteinuria) is seen in patients with light chain myeloma, in approximately 50% of those with IgG and IgA myeloma, and in some patients with other lymphoproliferative disorders (eg, macroglobulinaemia) and plasma cell dyscrasias (amyloid). Entire paraprotein molecules may also be detected in serum. Urine protein dipsticks do not detect Bence-Jones protein. Hemosiderin Hemo siderin is present in diseases involving a true siderosis of kidney parenchyma (hemochromatosis).It is also present 2-3 days after an acute hemolytic episode that produces hemoglobinemia and hemoglobinuria. Hemosiderin granules are found in intact renal tubular epithelial cells or occasionally in casts and may also be seen extracellularly. Urobilinogen Interpretation of results will depend upon several factors: the variability of color perception; the presence or absence of inhibitory factors; the presence or absence of inhibitory factors typically found in urine, the specific gravity or the pH; and the lighting conditions under which the product is used.
Subscribe to:
Posts (Atom)